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Kat7tm1.1Avo
Targeted Allele Detail
Summary
Symbol: Kat7tm1.1Avo
Name: K(lysine) acetyltransferase 7; targeted mutation 1.1, Anne K Voss
MGI ID: MGI:4947690
Synonyms: Hbo1loxP
Gene: Kat7  Location: Chr11:95165085-95201072 bp, - strand  Genetic Position: Chr11, 59.01 cM
Alliance: Kat7tm1.1Avo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170405
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette leaving exon 1 floxed. (J:170405)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 23 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat7 Mutation:  147 strains or lines available
References
Original:  J:170405 Kueh AJ, et al., HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011 Feb;31(4):845-60
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory