Gt(ROSA)26Sortm1.1(Otx2)Daac
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1.1(Otx2)Daac |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Dario Acampora |
MGI ID: |
MGI:4887449 |
Synonyms: |
R26Otx2 |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1.1(Otx2)Daac page
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Germline Transmission: |
Earliest citation of germline transmission:
J:166896
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Parent Cell Line: |
E14TG2a.4 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1.1(Otx2)Daac expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Otx2 (MGI:97451) |
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Mutation details: A vector containing a floxed neo/STOP cassette followed by the mouse cDNA and an IRES-GFP. Cre-mediated recombination removed the neo/STOP cassette.
(J:166896)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:166896 Di Salvio M, et al., Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. Nat Neurosci. 2010 Dec;13(12):1481-8 |
All: |
2 reference(s) |
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