Rp2^{Gt(EUCJ0183f04)Hmgu}
Gene trapped Allele Detail

Summary

• Symbol: Rp2^{Gt(EUCJ0183f04)Hmgu}
• Name: retinitis pigmentosa 2 homolog; gene trap EUCJ0183f04, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:4874654
• Synonyms: Rp2h^-
• Gene: Rp2 Location: ChrX:20230720-20271892 bp, + strand Genetic Position: ChrX, 15.83 cM, cytoband A2
• Alliance: Rp2^{Gt(EUCJ0183f04)Hmgu} page

Mutation origin

• Mutant Cell Line: EUCJ0183f04
• Germline Transmission: Earliest citation of germline transmission: J:219642
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: FlipROSAbetageo
• Mutation details: A gene trap cassette inserted into the first intron of the gene, and is predicted to truncate the encoded protein after lysine 32 (K31). The trap contains long terminal repeats (LTR), a splice acceptor (SA), a beta-Geo selective cassette containing beta-galactosidase and neo genes. A pair of FRT and loxP recombination signals in antisense orientation flanks the beta-Geo cassette. (J:219642)
• Sequence Tags: Sequence tag details (3 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  EUCJ0183f04.3SPK	HR712783 ; (MGI Seq Detail)	3'Splinkerette PCR	ChrX:20236345-20237028 bp (+)
  EUCJ0183f04.5SPK	HR695045 ; (MGI Seq Detail)	5'Splinkerette PCR	unknown
  EUCJ0183f04.5SPK	HR706945 ; (MGI Seq Detail)	5'Splinkerette PCR	ChrX:20235708-20236332 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rp2 Mutation: 6 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)