Mafa^tm1Eyc
Targeted Allele Detail

Summary

• Symbol: Mafa^tm1Eyc
• Name: MAF bZIP transcription factor A; targeted mutation 1, Alain Eychene
• MGI ID: MGI:4868450
• Synonyms: mafA^flox
• Gene: Mafa Location: Chr15:75617339-75620077 bp, - strand Genetic Position: Chr15, 34.82 cM
• Alliance: Mafa^tm1Eyc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164344
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A FRT-flanked PGK-neo selection cassette resides downstream of the polyadenylation signal of the endogenous gene, and loxP sites are present 46 bp upstream of the ATG translation initiation codon and downstream of the neo cassette. The 3' loxP site is followed by the coding sequence for E. coli beta-galactosidase (lacZ) with a nuclear localization signal. (J:164344)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mafa Mutation: 20 strains or lines available

References

• Original: J:164344 Lecoin L, et al., MafA transcription factor identifies the early ret-expressing sensory neurons. Dev Neurobiol. 2010 Jun;70(7):485-97
• All: 2 reference(s)