Tg(SMN2)#Ahmb
Transgene Detail

Summary

• Symbol: Tg(SMN2)#Ahmb
• Name: transgene insertion, Arthur H M Burghes
• MGI ID: MGI:4849843
• Synonyms: hSMN2⁺
• Transgene: Tg(SMN2)#Ahmb Location: unknown
• Alliance: Tg(SMN2)#Ahmb page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A 35.5 kb genomic fragment containing human SMN2 used for the transgene. The transgene is ubiquitously expressed in all tissues examined by Northern blot analysis. Lines 89 and 566 were generated. A pound symbol (#) is used when no line number is designated. (J:60592)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:166545 Jodelka FM, et al., A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Hum Mol Genet. 2010 Dec 15;19(24):4906-17
• All: 4 reference(s)