Slc34a2^tm1.1Scc
Targeted Allele Detail

Summary

• Symbol: Slc34a2^tm1.1Scc
• Name: solute carrier family 34 (sodium phosphate), member 2; targeted mutation 1.1, Susan S Schiavi
• MGI ID: MGI:4847567
• Synonyms: Npt2b^fl
• Gene: Slc34a2 Location: Chr5:53206695-53229006 bp, + strand Genetic Position: Chr5, 28.92 cM
• Alliance: Slc34a2^tm1.1Scc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166317
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP flanked neo cassette was inserted upstream of exon 6, and an additional loxP site was inserted downstream of exon 6. Cre-mediated recombination removed the neo cassette leaving exon 6 floxed. (J:166317)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc34a2 Mutation: 39 strains or lines available

Notes

ES cell line = AMK06.

References

• Original: J:166317 Sabbagh Y, et al., Intestinal npt2b plays a major role in phosphate absorption and homeostasis. J Am Soc Nephrol. 2009 Nov;20(11):2348-58
• All: 3 reference(s)