Ep400^tm3.1Fuku
Targeted Allele Detail

Summary

• Symbol: Ep400^tm3.1Fuku
• Name: E1A binding protein p400; targeted mutation 3.1, Rikiro Fukunaga
• MGI ID: MGI:4845875
• Synonyms: mDom^delta
• Gene: Ep400 Location: Chr5:110812239-110918583 bp, - strand Genetic Position: Chr5, 53.69 cM, cytoband F
• Alliance: Ep400^tm3.1Fuku page

Loss of bone marrow hematopoietic cells in Ep400^tm3Fuku/Ep400^tm3.1Fuku Tg(Mx1-cre)1Cgn/0 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166397
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Cre mediated recombination removed exon 15 and the neo cassette. (J:166397)

Generation of the Ep400^tm3Fuku and Ep400^tm3.1Fuku alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ep400 Mutation: 140 strains or lines available

References

• Original: J:166397 Fujii T, et al., Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progression. J Biol Chem. 2010 Sep 24;285(39):30214-23
• All: 1 reference(s)