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Creb3l1tm1e(EUCOMM)Wtsi
Targeted Allele Detail
Summary
Symbol: Creb3l1tm1e(EUCOMM)Wtsi
Name: cAMP responsive element binding protein 3-like 1; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:4842311
Gene: Creb3l1  Location: Chr2:91812673-91854515 bp, - strand  Genetic Position: Chr2, 50.63 cM, cytoband E1
Alliance: Creb3l1tm1e(EUCOMM)Wtsi page
IMPC: Creb3l1 gene page
Mutation
origin
Mutant Cell Lines:  EPD0651_2_A12, EPD0651_2_B03, EPD0651_2_B05, EPD0651_2_C01, EPD0651_2_C11, EPD0651_2_D01, EPD0651_2_D04, EPD0651_2_D09, EPD0651_2_D10, EPD0651_2_E04, EPD0651_2_E07, EPD0651_2_F05, EPD0651_2_F11, EPD0651_2_F12, EPD0651_2_G06, EPD0651_2_G10, EPD0651_2_H07
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 91832818 of Chromosome 2 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Creb3l1 Mutation:  54 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory