Vcantm1.1Hwat
Targeted Allele Detail
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Symbol: |
Vcantm1.1Hwat |
Name: |
versican; targeted mutation 1.1, Hideto Watanabe |
MGI ID: |
MGI:4840040 |
Synonyms: |
Vcanflox |
Gene: |
Vcan Location: Chr13:89803431-89890628 bp, - strand Genetic Position: Chr13, 45.5 cM
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Alliance: |
Vcantm1.1Hwat page
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Limb deformities in Vcantm1.1Hwat/Vcantm1.1Hwat Tg(Prrx1-cre)1Cjt/0 mice
Show the 5 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:165936
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette leaving exon 2 floxed.
(J:165936)
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Generation of the Vcantm1.1Hwat allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Vcan Mutation: |
164 strains or lines available
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Original: |
J:165936 Choocheep K, et al., Versican facilitates chondrocyte differentiation and regulates joint morphogenesis. J Biol Chem. 2010 Jul 2;285(27):21114-25 |
All: |
4 reference(s) |
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