Bclaf1^tm1Lfmp
Targeted Allele Detail

Summary

• Symbol: Bclaf1^tm1Lfmp
• Name: BCL2-associated transcription factor 1; targeted mutation 1, Leibniz-Institute of Molecular Pharmacology
• MGI ID: MGI:4839481
• Gene: Bclaf1 Location: Chr10:20187897-20218390 bp, + strand Genetic Position: Chr10, 9.75 cM, cytoband A3
• Alliance: Bclaf1^tm1Lfmp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP-flanked cassette containg a splice acceptor and beta-geo (E. coli beta-galactosidase (lacZ)/neomycin phosphotransferase fusion gene) has been inserted into the third intron of the gene, whose translation initiation codon is in exon 3. The gene is functionally inactive except in tissues/cells where Cre recombinase is expressed. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Bclaf1 Mutation: 61 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 2 reference(s)