Gli1^tm4Alj
Targeted Allele Detail

Summary

• Symbol: Gli1^tm4Alj
• Name: GLI-Kruppel family member GLI1; targeted mutation 4, Alexandra L Joyner
• MGI ID: MGI:4838602
• Synonyms: Gli1^eGFP
• Gene: Gli1 Location: Chr10:127165751-127177448 bp, - strand Genetic Position: Chr10, 74.5 cM
• Alliance: Gli1^tm4Alj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165495
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting construct inserted downstream of the translation start codon an EGFP, Gli1 3'UTR, polyadenylation sequences and floxed neomycin resistance cassette.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gli1 Mutation: 48 strains or lines available

References

• Original: J:165495 Garcia AD, et al., Sonic hedgehog regulates discrete populations of astrocytes in the adult mouse forebrain. J Neurosci. 2010 Oct 13;30(41):13597-608
• All: 5 reference(s)