Etv1tm1.1(cre/ERT2)Zjh
Targeted Allele Detail
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Symbol: |
Etv1tm1.1(cre/ERT2)Zjh |
Name: |
ets variant 1; targeted mutation 1.1, Z Josh Huang |
MGI ID: |
MGI:4838417 |
Synonyms: |
ER81-CreER, Er81-CreER-KI, ER81-CreERT2, Etv1-CreER, Etv1-CreERT2 |
Gene: |
Etv1 Location: Chr12:38829655-38920484 bp, + strand Genetic Position: Chr12, 17.99 cM
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Alliance: |
Etv1tm1.1(cre/ERT2)Zjh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:151755
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Project Collection: |
Neuroscience Blueprint cre
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Etv1tm1.1(cre/ERT2)Zjh expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Etv1 (MGI:99254) |
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Mutation details: A targeting vector was designed to insert a Cre/ERT2 fusion gene , an SV40 polyA signal, and an frt-flanked neo cassette into the initiation codon of the ets variant gene 1 locus (Etv1). This construct was electroporated into C57BL/6-derived embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts and chimeric mice were bred with white C57BL/6 mice (harboring the Tyrc-2J mutation) to originate the colony. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette.
(J:151755)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Etv1
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009; |
All: |
24 reference(s) |
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