Gata2^tm3.1Sho
Targeted Allele Detail

Summary

• Symbol: Gata2^tm3.1Sho
• Name: GATA binding protein 2; targeted mutation 3.1, Stuart Orkin
• MGI ID: MGI:4837902
• Synonyms: Gata2 delta -1.8
• Gene: Gata2 Location: Chr6:88170873-88184014 bp, + strand Genetic Position: Chr6, 39.2 cM
• Alliance: Gata2^tm3.1Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165427
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

Allele Type: Targeted Mutations: Insertion, Intragenic deletion Mutation details: The -1.8 kb Gata1 binding site was replaced with a floxed neo cassette. Cre mediated recombination removed the neo cassette. (J:165427)

Generation of the Gata2^tm3.1Sho allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata2 Mutation: 26 strains or lines available

References

• Original: J:165427 Snow JW, et al., A single cis element maintains repression of the key developmental regulator Gata2. PLoS Genet. 2010;6(9)
• All: 2 reference(s)