Igfbp7^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Igfbp7^tm1Vlcg
• Name: insulin-like growth factor binding protein 7; targeted mutation 1, Velocigene
• MGI ID: MGI:4836178
• Synonyms: AGM^lacZ
• Gene: Igfbp7 Location: Chr5:77497092-77555892 bp, - strand Genetic Position: Chr5, 41.71 cM
• Alliance: Igfbp7^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164939
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ cassette was inserted into the locus. Expression is detected in the vasculature of developing embryos and adult organs. (J:164939)

Expression

In Mice Carrying this Mutation:

25 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igfbp7 Mutation: 18 strains or lines available

References

• Original: J:164939 Hooper AT, et al., Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis. Circ Res. 2009 Jul 17;105(2):201-8
• All: 3 reference(s)