Scn1b^tm1.2Bion
Targeted Allele Detail

Summary

• Symbol: Scn1b^tm1.2Bion
• Name: sodium channel, voltage-gated, type I, beta; targeted mutation 1.2, Bionomics Limited
• MGI ID: MGI:4829976
• Gene: Scn1b Location: Chr7:30815949-30826428 bp, - strand Genetic Position: Chr7, 19.3 cM
• Alliance: Scn1b^tm1.2Bion page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163771
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre mediated recombination removed exon 3 and the neo cassette. (J:163771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scn1b Mutation: 8 strains or lines available

References

• Original: J:163771 Wimmer VC, et al., Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. J Clin Invest. 2010 Aug 2;120(8):2661-71
• All: 1 reference(s)