Tg(ACTB-SOD2)#Dksc
Transgene Detail

Summary

• Symbol: Tg(ACTB-SOD2)#Dksc
• Name: transgene insertion, Daret K St Clair
• MGI ID: MGI:4829816
• Transgene: Tg(ACTB-SOD2)#Dksc Location: unknown
• Alliance: Tg(ACTB-SOD2)#Dksc page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-SOD2)#Dksc expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SOD2 (6648)

  Sod2	(MGI:98352)

• Mutation details: A cDNA for human MnSOD was placed under the control of human beta Actin 5' flanking sequence and promoter. Three transgene lines were produced and maintained. (J:130288)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:130288 Yen HC, et al., The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J Clin Invest. 1996 Sep 1;98(5):1253-60
• All: 5 reference(s)