Col4a2^ENU415
Chemically induced Allele Detail

Summary

• Symbol: Col4a2^ENU415
• Name: collagen, type IV, alpha 2; ENU mutation 415
• MGI ID: MGI:4822169
• Gene: Col4a2 Location: Chr8:11362805-11499287 bp, + strand Genetic Position: Chr8, 5.62 cM
• Alliance: Col4a2^ENU415 page

Mutation origin

• Strain of Origin: (101 x C3H)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Ten to 12 week old male mice were exposed to a single interperitoneal dose of 250mg of ENU per kg of body weight. This resulted in a G to T nucleotide replacement at position 227 (NCBI accession # NJ:163225)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Col4a2 Mutation: 74 strains or lines available

References

• Original: J:21950 Favor J, A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea. Mutat Res. 1983 Aug;110(2):367-82
• All: 3 reference(s)