Col4a1^ENU911
Chemically induced Allele Detail

Summary

• Symbol: Col4a1^ENU911
• Name: collagen, type IV, alpha 1; ENU mutation 911
• MGI ID: MGI:4822141
• Gene: Col4a1 Location: Chr8:11248423-11362826 bp, - strand Genetic Position: Chr8, 5.53 cM
• Alliance: Col4a1^ENU911 page

Mutation origin

• Strain of Origin: (102 x C3H)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Ten to 12 week old male mice were exposed to a singles intraperitoneal dose of ENU. A G to T nucleotide substitution at position 2866 (NCBI accession # NM_009931) results in a Glycine to Valine substitution at amino acid residue 912. (J:163225)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Col4a1 Mutation: 77 strains or lines available

References

• Original: J:21951 Favor J, The frequency of dominant cataract and recessive specific-locus mutations in mice derived from 80 or 160 mg ethylnitrosourea per kg body weight treated spermatogonia. Mutat Res. 1986 Aug;162(1):69-80
• All: 3 reference(s)