Tg(FBN1*C1663R)F2Hcd
Transgene Detail

Summary

• Symbol: Tg(FBN1*C1663R)F2Hcd
• Name: transgene insertion F2, Harry C Dietz
• MGI ID: MGI:4820739
• Synonyms: Tg(mut3)
• Transgene: Tg(FBN1*C1663R)F2Hcd Location: unknown
• Alliance: Tg(FBN1*C1663R)F2Hcd page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:91349
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(FBN1*C1663R)F2Hcd expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FBN1 (2200)

  Fbn1	(MGI:95489)

• Mutation details: The transgene is composed of a YAC containing the full-length C1663R mutant human fibrillin 1 gene, including the promoter. Line F2 was generated. (J:91349)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:91349 Judge DP, et al., Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome. J Clin Invest. 2004 Jul;114(2):172-81
• All: 1 reference(s)