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Targeted Allele Detail
Symbol: Nacatm1(KOMP)Mbp
Name: nascent polypeptide-associated complex alpha polypeptide; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID: MGI:4819979
Gene: Naca  Location: Chr10:127871444-127884506 bp, + strand  Genetic Position: Chr10, 76.39 cM, cytoband D2-D3
IMPC: Naca gene page
Mutant Cell Lines:  DEPD00529_7_A01, DEPD00529_7_B01, DEPD00529_7_B03, DEPD00529_7_B04, DEPD00529_7_C02, DEPD00529_7_C03, DEPD00529_7_D01, DEPD00529_7_D02, DEPD00529_7_D03, DEPD00529_7_D04, DEPD00529_7_E01, DEPD00529_7_E04, DEPD00529_7_F01, DEPD00529_7_F02, DEPD00529_7_F03, DEPD00529_7_G01, DEPD00529_7_G03, DEPD00529_7_G04, DEPD00529_7_H01, DEPD00529_7_H04
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 232 starting at position 127872312 and ending at position 127872544 of Chromosome 10 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Naca Mutation:  164 strains or lines available
Original:  J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory