Tg(Tek-B4galnt2)1108Dgi
Transgene Detail

Summary

• Symbol: Tg(Tek-B4galnt2)1108Dgi
• Name: transgene insertion 1108, David Ginsburg
• MGI ID: MGI:4819742
• Synonyms: Tie2-B4galnt2
• Transgene: Tg(Tek-B4galnt2)1108Dgi Location: unknown
• Alliance: Tg(Tek-B4galnt2)1108Dgi page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tek-B4galnt2)1108Dgi expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	B4galnt2 (MGI:1342058)

• Mutation details: A transgenic vector was generated to include the endothelial-specific receptor tyrosine kinase (Tek) driving vascular endothelial specific expression of beta-1,4-N-acetyl-galactosaminyl transferase 2 (B4galnt2), followed by a simian virus 40 intron and a polyadenylation signal (polyA). This transgene is lacking 23 bp of B4galnt2 3'UTR for detection purposes. Line 1108 was established. (J:52069)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:52069 Mohlke KL, et al., Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell. 1999 Jan 8;96(1):111-20
• All: 1 reference(s)