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Tg(Actb-GFP,-luc)#Nki
Transgene Detail
Summary
Symbol: Tg(Actb-GFP,-luc)#Nki
Name: transgene insertion, The Netherlands Cancer Institute
MGI ID: MGI:4818466
Synonyms: LucRep
Transgene: Tg(Actb-GFP,-luc)#Nki  Location: unknown  
Alliance: Tg(Actb-GFP,-luc)#Nki page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe beta actin promoter is used to drive expression of either GFP or luciferase. The floxed GFP contains a polyadenylation sequence and is located upstream of the luciferase construct which also contains a polyadenylation sequence. Luciferase is not expressed until GFP is excised by cre. (J:86565)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86565 Lyons SK, et al., The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice. Cancer Res. 2003 Nov 1;63(21):7042-6
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory