Slc6a9tm1.1Veul
Targeted Allele Detail
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Symbol: |
Slc6a9tm1.1Veul |
Name: |
solute carrier family 6 (neurotransmitter transporter, glycine), member 9; targeted mutation 1.1, Volker Eulenburg |
MGI ID: |
MGI:4818449 |
Synonyms: |
GlyT- |
Gene: |
Slc6a9 Location: Chr4:117692240-117726502 bp, + strand Genetic Position: Chr4, 53.62 cM
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Alliance: |
Slc6a9tm1.1Veul page
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Germline Transmission: |
Earliest citation of germline transmission:
J:161993
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A floxed neomycin selection cassette was inserted in intron 2 and a third loxP was inserted in intron 4. The neomycin selection cassette was then removed by transient cre expression leaving exons 3 and 4 floxed. Subsequently, mice were crossed to Tg(EIIa-cre)C5379Lmgd mice to excise exons 3 and 4 creating a knockout allele.
(J:161993)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc6a9 Mutation: |
24 strains or lines available
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Original: |
J:161993 Eulenburg V, et al., Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice. Glia. 2010 Jul;58(9):1066-73 |
All: |
1 reference(s) |
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