Sufu^tm1Blnw
Targeted Allele Detail

Summary

• Symbol: Sufu^tm1Blnw
• Name: SUFU negative regulator of hedgehog signaling; targeted mutation 1, Baolin Wang
• MGI ID: MGI:4461192
• Synonyms: Sufu^flox
• Gene: Sufu Location: Chr19:46385335-46477243 bp, + strand Genetic Position: Chr19, 38.85 cM
• Alliance: Sufu^tm1Blnw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161408
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 1, and an additional loxP site was inserted downstream of exon 1. (J:161408)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sufu Mutation: 59 strains or lines available

References

• Original: J:161408 Wang C, et al., Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development. 2010 Jun;137(12):2001-9
• All: 1 reference(s)