Zbtb16^7t
Chemically induced Allele Detail

Summary

• Symbol: Zbtb16^7t
• Name: zinc finger and BTB domain containing 16; seven toes
• MGI ID: MGI:4457499
• Synonyms: 7t, Plzf^7t
• Gene: Zbtb16 Location: Chr9:48565597-48747522 bp, - strand Genetic Position: Chr9, 26.47 cM
• Alliance: Zbtb16^7t page

Limb and axial skeleton abnormalities in Zbtb16^7t/Zbtb16^7t mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This ENU induced mutation has an A to G transition at nucleotide 379 of the cDNA, which alters amino acid 44 from the polar and acidic amino acid glutamic acid into the nonpolar neutral amino acid glycine (Glu44Gly). This amino acid resides in the conserved BTB (Bric-a-brac, Tramtrack, Broad-complex) or POZ (Poxvirus zinc finger) domain of the gene. (J:160477)

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zbtb16 Mutation: 30 strains or lines available

References

• Original: J:160477 Ching YH, et al., An allele separating skeletal patterning and spermatogonial renewal functions of PLZF. BMC Dev Biol. 2010;10(1):33
• All: 1 reference(s)