Mov10l1^tm1.1Eno
Targeted Allele Detail

Summary

• Symbol: Mov10l1^tm1.1Eno
• Name: Mov10 like RISC complex RNA helicase 1; targeted mutation 1.1, Eric N Olson
• MGI ID: MGI:4457212
• Synonyms: Mov10l1^fl
• Gene: Mov10l1 Location: Chr15:88867112-88939355 bp, + strand Genetic Position: Chr15, 44.49 cM
• Alliance: Mov10l1^tm1.1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161124
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 20 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 20. Flp mediated recombination removed the neo cassette leaving exon 20 floxed. (J:161124)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mov10l1 Mutation: 46 strains or lines available

References

• Original: J:161124 Frost RJ, et al., MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11847-52
• All: 10 reference(s)