Trp53tm1.1Rivm
Targeted Allele Detail
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Symbol: |
Trp53tm1.1Rivm |
Name: |
transformation related protein 53; targeted mutation 1.1, National Institute of Public Health and Environmental Protection (RIVM) |
MGI ID: |
MGI:4457011 |
Synonyms: |
TgH(Tp53.hex4.72R)rivm, Trp53tm1.1Hvs |
Gene: |
Trp53 Location: Chr11:69471185-69482699 bp, + strand Genetic Position: Chr11, 42.83 cM, cytoband B2-C
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Alliance: |
Trp53tm1.1Rivm page
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Germline Transmission: |
Earliest citation of germline transmission:
J:94077
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted |
Mutation: |
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Insertion
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Mutation details: This allele contains exon 4 of the human TRP53 gene, with the human arginine variant at codon 72 (dbSNP:rs1042522; 72R). Codon 270, in the unmodified exon 8 - corresponding to human TRP53 codon 273 - encodes arginine (270R; mouse wild-type). A single loxP site in intron 1 is retained from an excised loxP-flanked translational STOP and selection cassette.
(J:94077)
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Original: |
J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015; |
All: |
1 reference(s) |
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