Pdia3^{Gt(RST003)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Pdia3^{Gt(RST003)Byg}
• Name: protein disulfide isomerase associated 3; gene trap RST003
• MGI ID: MGI:4456212
• Synonyms: ERp57^-
• Gene: Pdia3 Location: Chr2:121244383-121269168 bp, + strand Genetic Position: Chr2, 60.38 cM
• Alliance: Pdia3^{Gt(RST003)Byg} page

Mutation origin

• Mutant Cell Line: RST003
• Germline Transmission: Earliest citation of germline transmission: J:160036
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Gene trapped (Null/knockout, Reporter) Mutation: Insertion of gene trap vector Vector: pGT1.8TM Vector Type: secretory trap Mutation details: The gene trap vector inserted between exon 4 and 5. The absence of protein expression was confirmed by western blot analysis. (J:160036)

Generation of the Pdia3^Gt(RST003)Byg allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdia3 Mutation: 37 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:160036 Coe H, et al., ERp57 modulates STAT3 signaling from the lumen of the endoplasmic reticulum. J Biol Chem. 2010 Feb 26;285(9):6725-38
• All: 2 reference(s)