Stard4^tm1.1Bres
Targeted Allele Detail

Summary

• Symbol: Stard4^tm1.1Bres
• Name: StAR related lipid transfer domain containing 4; targeted mutation 1.1, Jan L Breslow
• MGI ID: MGI:4456142
• Gene: Stard4 Location: Chr18:33332408-33346915 bp, - strand Genetic Position: Chr18, 18.18 cM
• Alliance: Stard4^tm1.1Bres page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160807
• Parent Cell Line: CY2.4 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A targeting vector containing an FRT site flanked NEO cassette was utilized in the construction of this mutant. This selection cassette was inserted downstream of exon 3 of the targeted gene, and loxP sites were placed flanking exon 3. Flp mediated recombination removed the neo cassette leaving exon 3 floxed. (J:160807)

Generation of the Stard4^tm1.1Bres and Stard4^tm1.2Bres alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stard4 Mutation: 16 strains or lines available

References

• Original: J:160807 Riegelhaupt JJ, et al., Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism. J Lipid Res. 2010 May;51(5):1134-43
• All: 1 reference(s)