Tg(tetO-Gnaq*R183C)1Conk
Transgene Detail

Summary

• Symbol: Tg(tetO-Gnaq*R183C)1Conk
• Name: transgene insertion 1, Bruce R Conklin
• MGI ID: MGI:4455195
• Synonyms: tetO-Gq*
• Transgene: Tg(tetO-Gnaq*R183C)1Conk Location: unknown
• Alliance: Tg(tetO-Gnaq*R183C)1Conk page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Constitutively active, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: This transgene contains the tetracycline responsive element (TRE) driving expression, from a minimal promoter, of a mutant guanine nucleotide-binding protein, alpha q polypeptide (alpha q) in which the arginine at amino acid position 183 has been replaced by cysteine (R183C). This constitutively active mutant protein maintains phospholipase C in an active state. It is expressed in the presence of tTA without tetracycline (tet-off) or in the presence of rtTA and tetracycline (tet-on), (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)