Tg(tetO-ptxA)1Conk
Transgene Detail

Summary

• Symbol: Tg(tetO-ptxA)1Conk
• Name: transgene insertion 1, Bruce R Conklin
• MGI ID: MGI:4455185
• Synonyms: tetO-PTX, Tg(tetO-PTX)1Conk
• Transgene: Tg(tetO-ptxA)1Conk Location: unknown
• Alliance: Tg(tetO-ptxA)1Conk page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: This transgene contains the tetracycline transactivator responsive element (TRE) driving expression, from a minimal promoter, of the catalytic S1 subunit of pertussis toxin, encoded by ptxA. This permits tTA (tet-off) or rtTA (tet-on) to induce expression of PTX-S1, which blocks signaling via the pertussis toxin-sensitive G proteins (Gi and Go). (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 3 reference(s)