Tg(NKX2-5-EmGFP)2Conk
Transgene Detail
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| Symbol: |
Tg(NKX2-5-EmGFP)2Conk |
| Name: |
transgene insertion 2, Bruce Conklin |
| MGI ID: |
MGI:4454777 |
| Synonyms: |
RP11-88L12 NKX-2.5-EmGFP |
| Transgene: |
Tg(NKX2-5-EmGFP)2Conk Location: unknown
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| Alliance: |
Tg(NKX2-5-EmGFP)2Conk page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:160582
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| Parent Cell Line: |
E14TG2aIV (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The human BAC RP11-88L12 was modified to carry an in-frame P2A-Emerald GFP (EmGFP) insertion, a Zeocin cassette, and an SV40-Neo selection cassette. Expression is detected in early cardiac progenitors, embryonic heart tissues, and other tissues expressing NKX2-5 (e.g. foregut and branchial arches). Two lines were generated (lines 1 and 2).
(J:160582)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:160582 Hsiao EC, et al., Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter. PLoS One. 2008;3(7):e2532 |
| All: |
4 reference(s) |
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Analysis Tools
