Bdnf^tm1Yab
Targeted Allele Detail

Summary

• Symbol: Bdnf^tm1Yab
• Name: brain derived neurotrophic factor; targeted mutation 1, Yves-Alain Barde
• MGI ID: MGI:4443014
• Synonyms: bdnf^lox
• Gene: Bdnf Location: Chr2:109505045-109557352 bp, + strand Genetic Position: Chr2, 56.63 cM
• Alliance: Bdnf^tm1Yab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The single protein coding exon, exon 9, was flanked by loxP sites. (J:157932)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bdnf Mutation: 41 strains or lines available

References

• Original: J:157932 Rauskolb S, et al., Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. J Neurosci. 2010 Feb 3;30(5):1739-49
• All: 9 reference(s)