Tg(Igh-VR16.7/Igh-C)5Sls
Transgene Detail

Summary

• Symbol: Tg(Igh-VR16.7/Igh-C)5Sls
• Name: transgene insertion 5, Erik Selsing
• MGI ID: MGI:4442646
• Synonyms: Tg.ARSmu
• Transgene: Tg(Igh-VR16.7/Igh-C)5Sls Location: unknown Genetic Position: Chr5, Syntenic
• Alliance: Tg(Igh-VR16.7/Igh-C)5Sls page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh-VR16.7/Igh-C)5Sls expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igh (MGI:96442)

• Mutation details: The re-arranged VDJ gene segment isolated from the CRIa hybridoma R16.7 was fused to a Cmu gene segment obtained from a BALB/c genomic clone. Four transgenic founders were reported. most initial work was done on lines 5 and 33 while lines 23 and 35 were only studied to a limited extend. Line 5 was used in at least one subsequenty paper. Line 5 contains about 50 copies of the insert. (J:132265)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132265 Durdik J, et al., Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice. Proc Natl Acad Sci U S A. 1989 Apr;86(7):2346-50
• All: 2 reference(s)