Tg(CAG-rtTA)356Ahay
Transgene Detail

Summary

• Symbol: Tg(CAG-rtTA)356Ahay
• Name: transgene insertion 356, Adrian C Hayday
• MGI ID: MGI:4442162
• Transgene: Tg(CAG-rtTA)356Ahay Location: unknown
• Alliance: Tg(CAG-rtTA)356Ahay page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The reverse tetracycline-dependent transcriptional activator (rtTA-VP16) was placed under the control of the CAG ubiquitous promoter. (J:100454)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:100454 Oppenheim DE, et al., Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance. Nat Immunol. 2005 Sep;6(9):928-37
• All: 1 reference(s)