Cryaa^tm2Ady
Targeted Allele Detail

Summary

• Symbol: Cryaa^tm2Ady
• Name: crystallin, alpha A; targeted mutation 2, Usha P Andley
• MGI ID: MGI:4437473
• Synonyms: Cryaa^WTneo
• Gene: Cryaa Location: Chr17:31896905-31900704 bp, + strand Genetic Position: Chr17, 17.09 cM, cytoband A3-B
• Alliance: Cryaa^tm2Ady page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157274
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• A floxed neo cassette was inserted downstream of exon 1. (J:157274)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cryaa Mutation: 14 strains or lines available

References

• Original: J:157274 Andley UP, AlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice. BMC Ophthalmol. 2009;9:4
• All: 1 reference(s)