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Igs1tm3(CAG-Bgeo,-tdTomato/TEVP,-Dlg4,-GFP)Nat
Targeted Allele Detail
Summary
Symbol: Igs1tm3(CAG-Bgeo,-tdTomato/TEVP,-Dlg4,-GFP)Nat
Name: intergenic site 1; targeted mutation 3, Jeremy Nathans
MGI ID: MGI:4430071
Synonyms: Iis1tm3(CAG-Bgeo,-tdTomato/TEVP,-Dlg4,-GFP)Nat, Ubbtm1(tdT-TEVP-PSD95-GFP)Nat, Ubbtm3Nat
Gene: Igs1  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance: Igs1tm3(CAG-Bgeo,-tdTomato/TEVP,-Dlg4,-GFP)Nat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157150
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change, Reporter)
Mutation:    Insertion
 
Mutation detailsThe following elements were inserted in order into 2 kb upstream of the Ubb locus by targeted recombination: CMV enhancer/beta-actin promoter (CAG), loxP site, beta-geo, 3 stop transcription sites, loxP site, tdTomato/Tobacco etch virus protease (TEVP), a 6xmyc epitope, a TEVP cleavage site, post-synaptic density protein (PSD95), GFP, 3xHA epitope, rabbit beta-globin 3' UTR. (J:157150)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igs1 Mutation:  10 strains or lines available
References
Original:  J:157150 Nathans J, Direct Submission of Ubbtm3Nat. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory