Rr4^tm1Hgc
Targeted Allele Detail

Summary

• Symbol: Rr4^tm1Hgc
• Name: regulatory region 4; targeted mutation 1, Edward M Rubin
• MGI ID: MGI:4421037
• Synonyms: uc482^-
• Gene: Rr4 Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Rr4^tm1Hgc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128347
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The conserved nucleotide sequence was replaced with a floxed neomycin selection cassette. This selection cassette was subsequently excised from ES cells. (J:128347)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rr4 Mutation: 2 strains or lines available

References

• Original: J:128347 Ahituv N, et al., Deletion of ultraconserved elements yields viable mice. PLoS Biol. 2007 Sep;5(9):e234
• All: 1 reference(s)