Chmp1b2^{tm1(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Chmp1b2^{tm1(KOMP)Wtsi}
• Name: charged multivesicular body protein 1B2; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:4420098
• Gene: Chmp1b2 Location: ChrX:106826357-106859940 bp, - strand Genetic Position: ChrX, 47.62 cM
• IMPC: Chmp1b2 gene page

Mutation origin

• Mutant Cell Line: EPD0410_5_G09
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 797 starting at position 106836497 and ending at position 106837294 of Chromosome X (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chmp1b2 Mutation: 2 strains or lines available

References

• Original: J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009
• All: 2 reference(s)