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Srsf6tm1(KOMP)Wtsi
Targeted Allele Detail
Summary
Symbol: Srsf6tm1(KOMP)Wtsi
Name: serine and arginine-rich splicing factor 6; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:4419754
Gene: Srsf6  Location: Chr2:162773448-162779041 bp, + strand  Genetic Position: Chr2, 83.87 cM
IMPC: Srsf6 gene page
Mutation
origin
Mutant Cell Lines:  EPD0387_2_A05, EPD0387_2_F05, EPD0387_2_H07
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 2780 starting at position 162773912 and ending at position 162776692 of Chromosome 2 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Srsf6 Mutation:  33 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory