Atp8b2tm1e(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Atp8b2tm1e(KOMP)Wtsi |
Name: |
ATPase, class I, type 8B, member 2; targeted mutation 1e, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4419288 |
Gene: |
Atp8b2 Location: Chr3:89846795-89870645 bp, - strand Genetic Position: Chr3, 39.19 cM, cytoband F2
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IMPC: |
Atp8b2 gene page |
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Mutant Cell Lines: |
EPD0367_6_A10, EPD0367_6_A11, EPD0367_6_A12, EPD0367_6_B10, EPD0367_6_B12, EPD0367_6_C09, EPD0367_6_C10, EPD0367_6_C11, EPD0367_6_E09, EPD0367_6_E10, EPD0367_6_E12, EPD0367_6_F09, EPD0367_6_F11, EPD0367_6_F12, EPD0367_6_G09, EPD0367_6_G10, EPD0367_6_G11, EPD0367_6_H09, EPD0367_6_H10, EPD0367_6_H11, EPD0367_6_H12 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 89856619 of Chromosome 3 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:148605, J:173534)
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
2 reference(s) |
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