G6pc1tm2.2Jyc
Targeted Allele Detail
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Symbol: |
G6pc1tm2.2Jyc |
Name: |
glucose-6-phosphatase catalytic subunit 1; targeted mutation 2.2, Janice Yang Chou |
MGI ID: |
MGI:4418685 |
Synonyms: |
G6pcdelta |
Gene: |
G6pc1 Location: Chr11:101258542-101268729 bp, + strand Genetic Position: Chr11, 64.83 cM
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Alliance: |
G6pc1tm2.2Jyc page
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Glycogen accumulation in hepatocytes and tubular epithelial cells of the kidney in G6pc1tm2.2Jyc/G6pc1tm2.2Jyc mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:155990
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 3 was floxed and a FRT neo cassette was inserted within intron 3 by homologous recombination. The selection cassette was removed by flp-mediated recombination. Exon 3 was removed by cre-mediated recombination. No detectable G6Pase enzymatic activities are seen in the liver and kidney.
(J:155990)
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Generation of the G6pc1tm2Jyc, G6pc1tm2.1Jyc, and G6pc1tm2.2Jyc alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any G6pc1 Mutation: |
18 strains or lines available
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Original: |
J:155990 Peng WT, et al., Generation of mice with a conditional allele for G6pc. Genesis. 2009 Sep;47(9):590-4 |
All: |
1 reference(s) |
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