Tg(Hes7-cre)1Kag
Transgene Detail
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Symbol: |
Tg(Hes7-cre)1Kag |
Name: |
transgene insertion 1, Ryoichiro Kageyama |
MGI ID: |
MGI:4415616 |
Synonyms: |
Hes7-Cre (Acc. No. CDB0551T) |
Transgene: |
Tg(Hes7-cre)1Kag Location: unknown
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Alliance: |
Tg(Hes7-cre)1Kag page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Hes7-cre)1Kag expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Hes7 |
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Mutation details: Nuclear localizing Cre recombinase is expressed under control of a 5.4-kb genomic DNA fragment containing the Hes7 (hairy and enhancer of split 7 (Drosophila)) promoter. Cre mRNA is expressed in the presomitic mesoderm (PSM) of the E10.5 embryo, and its expression appears to oscillate. In doubly transgenic embryos bearing this transgene and a lacZ reporter transgene, X-gal staining is observed throughout the PSM and in the somites and their derivatives at E7.5-E10.5.
(J:124102)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Hes7
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:124102 Niwa Y, et al., The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell. 2007 Aug;13(2):298-304 |
All: |
3 reference(s) |
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