Ezh2^tm1Yugo
Targeted Allele Detail

Summary

• Symbol: Ezh2^tm1Yugo
• Name: enhancer of zeste 2 polycomb repressive complex 2 subunit; targeted mutation 1, Yukiko Gotoh
• MGI ID: MGI:4412411
• Synonyms: Ezh2deltaset^f, Ezh2^SET-fl
• Gene: Ezh2 Location: Chr6:47507073-47572275 bp, - strand Genetic Position: Chr6, 22.92 cM, cytoband B
• Alliance: Ezh2^tm1Yugo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154927
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 18 and an additional loxP site was inserted downstream of exon 19. (J:154927)

Expression

In Mice Carrying this Mutation:

4 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ezh2 Mutation: 71 strains or lines available

References

• Original: J:154927 Hirabayashi Y, et al., Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron. 2009 Sep 10;63(5):600-13
• All: 28 reference(s)