Tg(Sox10-cre)507Mcln
Transgene Detail

Summary

• Symbol: Tg(Sox10-cre)507Mcln
• Name: transgene insertion 507, Andrew S McCallion
• MGI ID: MGI:4410448
• Synonyms: SF4:Cre, Tg(Sox10-cre)1Mcln
• Transgene: Tg(Sox10-cre)507Mcln Location: unknown
• Alliance: Tg(Sox10-cre)507Mcln page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Sox10-cre)507Mcln expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Sox10

• Mutation details: The Sox10 Multiple Species Conserved Sequence 4 (MCS 4) enhancer sequence located 28.5 kb upstream of the transcriptional start site was placed in front of the Fos (c-fos) minimal promoter to drive the cre open reading frame and polyadenylation sequence. The construct was injected into pronuclei of B6SJLF1 oocytes. (J:154787)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox10 (species not specified) Summary of all recombinase alleles driven by Sox10. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:154787 Stine ZE, et al., Oligodendroglial and pan-neural crest expression of Cre recombinase directed by Sox10 enhancer. Genesis. 2009 Nov;47(11):765-70
• All: 5 reference(s)