Sin3b^tm1.1Rdp
Targeted Allele Detail

Summary

• Symbol: Sin3b^tm1.1Rdp
• Name: transcriptional regulator, SIN3B (yeast); targeted mutation 1.1, Ronald dePinho
• MGI ID: MGI:4410334
• Synonyms: mSin3B^L
• Gene: Sin3b Location: Chr8:73449913-73484829 bp, + strand Genetic Position: Chr8, 35.08 cM, cytoband C2
• Alliance: Sin3b^tm1.1Rdp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154855
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Sin3b^tm1Rdp mice were crossed to Tg(ACTFLPe)9205Dym to excise the Frt flanked neomycin cassette. Resulting mice express the floxed gene normally and display no gross phenotypic abnormalities. (J:154855)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sin3b Mutation: 49 strains or lines available

References

• Original: J:154855 David G, et al., Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4168-72
• All: 8 reference(s)