Omg^tm1.2Bzh
Targeted Allele Detail

Summary

• Symbol: Omg^tm1.2Bzh
• Name: oligodendrocyte myelin glycoprotein; targeted mutation 1.2, Binhai Zheng
• MGI ID: MGI:4399087
• Synonyms: OMgp^Flox
• Gene: Omg Location: Chr11:79391808-79394908 bp, - strand Genetic Position: Chr11, 46.79 cM, cytoband B5
• Alliance: Omg^tm1.2Bzh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154794
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: Germ line, flp mediated recombination removes the LacZ gene and neo cassette leaving exon 2 floxed. A 35% reduction in protein expression was confirmed by western blot analysis on extracts from homozygotes. (J:154794)

Generation of a series of Omg alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Omg Mutation: 20 strains or lines available

References

• Original: J:154794 Lee JK, et al., Generation of an OMgp allelic series in mice. Genesis. 2009 Nov;47(11):751-6
• All: 1 reference(s)