About   Help   FAQ
Lnpeptm1Sych
Targeted Allele Detail
Summary
Symbol: Lnpeptm1Sych
Name: leucyl/cystinyl aminopeptidase; targeted mutation 1, Siew Yeen Chai
MGI ID: MGI:4397579
Synonyms: IRAPlox
Gene: Lnpep  Location: Chr17:17747985-17846303 bp, - strand  Genetic Position: Chr17, 9.77 cM
Alliance: Lnpeptm1Sych page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154386
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 2, followed by a neo cassette, was floxed. (J:154386)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lnpep Mutation:  99 strains or lines available
References
Original:  J:154386 Albiston AL, et al., Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory. Neurobiol Learn Mem. 2010 Jan;93(1):19-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory