Ubr5^{Gt(EUCE0171f01)Hmgu}
Gene trapped Allele Detail

Summary

• Symbol: Ubr5^{Gt(EUCE0171f01)Hmgu}
• Name: ubiquitin protein ligase E3 component n-recognin 5; gene trap EUCE0171f01, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:4383314
• Synonyms: Ubr5^mt
• Gene: Ubr5 Location: Chr15:37967572-38079098 bp, - strand Genetic Position: Chr15, 15.1 cM
• Alliance: Ubr5^{Gt(EUCE0171f01)Hmgu} page

Mutation origin

• Mutant Cell Line: EUCE0171f01
• Germline Transmission: Earliest citation of germline transmission: J:236026
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rsFlipROSAbgeo*
• Mutation details: A conditional gene trap vector flanked by loxP, lox511 and FRT sites inserted between exons 20 and 21. The gene trap construct is designed such that in the absence of recombinase the gene trap resided in the mutagenic orientation (Ubr5^mt); (2) after flp-mediated recombination, in the non-mutagenic orientation (Ubr5^WT*); and (3) after cre-mediated recombination, in the permanent mutagenic orientation (Ubr5^mt*). (J:236026)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  EUCE0171f01.q1ka5SPK	FI567465 ; (MGI Seq Detail)	5'Splinkerette PCR	Chr15:38016642-38016854 bp (-)
  EUCE0171f01.p1kb3SPK	FI531371 ; (MGI Seq Detail)	3'Splinkerette PCR	Chr15:38016500-38016621 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  117 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubr5 Mutation: 119 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)