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Gene trapped Allele Detail
Symbol: Nmnat2Gt(EUCE0262a08)Hmgu
Name: nicotinamide nucleotide adenylyltransferase 2; gene trap EUCE0262a08, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:4371844
Synonyms: Nmnat2gt, Nmnat2gtE
Gene: Nmnat2  Location: Chr1:152830744-152995007 bp, + strand  Genetic Position: Chr1, 65.15 cM
Alliance: Nmnat2Gt(EUCE0262a08)Hmgu page
Hunched posture, failure to initiate respiration, and swollen bladders in E18.5 Nmnat2Gt(EUCE0262a08)Hmgu/Nmnat2Gt(RRF238)Byg pups

Show the 1 phenotype image(s) involving this allele.

Mutant Cell Line:  EUCE0262a08
Germline Transmission:  Earliest citation of germline transmission: J:192196
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: rsFlipROSAbgeo*
Mutation detailsThe gene trap cassette is flanked with FRT, F3, loxP and lox511 sites. The sites are oriented to allow for inversion of the gene trap cassette. The gene trap construct inserted into intron 1. Immunoblot analysis confirmed the absence of protein expression in brains from homozygous embryos at E13-E14.5, but a trace amount of mRNA was detected by RT-PCR. (J:200901)
Sequence Tags: 
Sequence tag details (2 tags)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmnat2 Mutation:  270 strains or lines available
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory